Our Passion for Patient Centricity
We conduct clinical trials visits in the patients at home, school or place of work, this offers a truly convenient way for patients to participate in clinical trials. Bringing the clinic to the patient builds an optimum relationship with study subjects, often the same nurse will visit regularly and build a better understanding of the subject's health. This service alleviates stress and improves the overall patient experience in studies where enrollment is typically an issue, for example in rare disease studies.
Aside from the benefits to the patient there are also great sponsor benefits. This service generally enhances recruitment rates as patients need to visit the site less regularly, it also enables those less mobile or who live in remote locations to participate. This approach to research nursing can also improve retention rates as patients build an open relationship with their visiting nurse. Compliance is respected and maintained throughout and visits which will be performed away from the sites are advised within the study protocol. These factors provide extra support to the patient whilst also enabling the drug to potentially reach the marketplace more quickly.
Examples of where utilising Illingworth’s mobile research nurses has had a tangible positive impact on the study:
- In one Chronic Cough study utilising mobile research nurses enabled us to recruit four times the number of patients in the UK compared to the US.
- Our research nurse dressed up like a fairy to give chemotherapy to a little girl who disliked her treatment, making the visit less stressful.
- In a Duchenne Muscular Dystrophy trial, children had three out of four of their injections performed at home, reducing the loss of school time and minimising the overall level of disruption for the family. Dropout of patients was reduced to zero in the two year period following Illingworth's involvement, completing recruitment in a difficult therapeutic area.
- Patients with terminal ovarian cancer were given the chance to spend precious time at home rather than going to site for simple blood draws.
Procedures Nurse May Perform Include:
Procedures which can be performed in the home (or work or school) setting include administration of study drug which may be intramuscular, via an intravenous infusion or oral etc.
IMP can be either collected by the homecare team from site pharmacies and transported to the subject or if a temperature controlled environment is necessary a courier can be used. Any blood samples taken may be processed and spun in the home and we can ship samples on dry ice as necessary.
Research nurses also complete CRF or e-CRFs, ECGs, completion of questionnaires, monitoring such as cough monitoring and spirometry to name but a few. This is an ideal method to minimise trips to the hospital and/or clinic for the subjects, whilst maintaining the high level of involvement usually required as part of a clinical trial. A home care manual is prepared to explain all the procedures to be performed at each specific visit timepoint. Full training is given to the nurse on this manual.
Our research nurses are flexible,within the protocol to perform visits either early in the morning, later in the evening after school or work or we can even conduct the visits at the patient’s work or school, in the case of children.
In order to support our team working in this way, we have an infrastructure in place to provide assistance as required, including remote technical support. A nurse Project Manager oversees each of our home research nursing projects. They liaise with the Sponsors, provide support to the nurses, help schedule patient visits, maintain the document trail and so on. Our nurse Project Managers are experienced nurses with clinical research experience and years of experience working in the Biopharmaceutical Industry.