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Respiratory

Illingworth  Research  Group  Limited  is  a  CRO   with   a   long   history   working   in   respiratory  clinical  trials including asthma, idiopathic pulmonary fibrosis and chronic refractory cough.

We have a specialist cough team are available to work on cough studies and this includes Project Managers, 7  UK based CRAs and 8   US based CRAs.

All members of this specialist team have extensive industry experience and experience of working with VitaloJAKs –   a 510(K) FDA  approved and CE marked custom-built digital recording device (VitaloJAK, Vitalograph Ltd) and currently the only FDA  approved cough monitor for use in clinical trials. Additionally,  we have conducted cough challenge studies involving the inhalation of tussive agents/substances such as ATP,   Capsaicin, Citric Acid and Distilled Water.   These substances were inhaled via a neubulizer,   controlled by the KoKo DigiDoser and the number of induced coughs counted.

Illingworth has  a  unique  set-up for specific respiratory studies,  engaging  with  selected  commercial  ‘super-sites’  in  the  UK  and  Europe,  giving  you  access  to  unprecedented  patient  numbers  to  take  part in these trials. These ‘super-sites’ have a  comprehensive  pedigree  in  respiratory  research and are considered experts in this therapeutic  area,  both  in  device  and  drug  studies.

Illingworth   Research   Group   has   many   highly    experienced    respiratory    Project   Managers  and  CRA’s  who  co-ordinate  the  submissions required to set up the studies within     these     sites.     Since     the     UK     ‘super-sites’   are   commercial   units   and  therefore  outside  of  the  National  Health  Service, they do not require R&D approvals and can, as a result, obtain decisions very rapidly  making  it  an  attractive  option  for sponsors.

Our  ‘super-site’  network  has  fully  trained  ARTP   physiologists   together   with   the latest equipment;

  • Body boxes
  • Various spirometers
  • Analysers
  • Oscillometry
  • Exercise challenge equipment
  • Lung clearance index
  • Challenge chambers
  • FeNO (nasal/exhaled) plus differential NO
  • Vibration resonance imaging
  • Exercise testing VO2 max
  • Central spirometry over reading
  • Doppler USS and 64 slice PET/ CT
  • Full endoscopy and bronchoscopy services
  • Biomarker laboratory

  Please click on the link below for the case study.